3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11082 | Dot1L-IN-2 | Histone Methyltransferase | |
Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectively. | |||
T63955 | MU1656 | ||
MU1656, a potent and selective histone methyltransferase DOT1L inhibitor, demonstrates an IC50 of 2 nM. It is applicable in the research of hematological malignancies [1]. | |||
T73637 | Dot1L-IN-1 TFA | ||
Dot1L-IN-1 TFA is a potent and selective Dot1L inhibitor, characterized by a K i of 2 pM and an IC 50 of <0.1 nM. It effectively inhibits H3K79 dimethylation (IC 50 =3 nM) and suppresses the HoxA9 promoter activity (IC 5... |